Acharya Prashant explains that absolute independence at the physical or natural level is impossible for a living being, as we are constantly dependent on the environment for basic needs like breath and food. He advises that one should not seek trivial independence in small matters or get into unnecessary conflicts with family or society. Instead, one should remain flexible and cooperative in worldly affairs, such as household chores or business, as long as they do not interfere with one's spiritual journey or relationship with the Truth. He emphasizes that the only area where one must never compromise is their inner liberation and devotion to the Divine.