Acharya Prashant explains that Shri Dattatreya is not calling transcendence a sin, but rather repenting for the human tendency to destroy that transcendence through limited religious practices. By going on a pilgrimage to a specific location, one acts as if the Divine is not all-pervasive. Similarly, using the mind and its methods for meditation treats the Truth as an object within the mind, thereby belittling its transcendent nature. The speaker emphasizes that any attempt to describe or praise the Divine is a profanity because it turns the profound into something graspable and petty, reducing the infinite to the level of the human ego.