Acharya Prashant addresses the question of whether it is possible to help those who are in deep blindness and refuse to acknowledge reality. He explains that blindness is synonymous with suffering because it is not our essential nature to be blind or ignorant. Our core nature is intelligence, understanding, and awareness. Even when a person pretends to be blind or justifies their ignorance through traditions and logic, their innermost core continues to suffer because it knows the truth. This suffering acts as a built-in defense mechanism and a call from the truth, signaling that something is wrong and needs correction, much like physical pain alerts the body to an injury.