Acharya Prashant explains a famous mantra from the Ishavasya Upanishad, which states that those who worship ignorance (avidya) enter deep darkness, but those who are devoted only to knowledge (vidya) enter into even deeper darkness. He notes that while people easily accept that worldly attachment leads to suffering, the idea that knowledge can lead to a worse state is shocking. He clarifies that 'avidya' refers to sensory experiences and the material world, which is a natural starting point for any human being born into time and space. Living in 'avidya' is common and expected for a person defined by their physical existence and ego.