Acharya Prashant explains that depression cannot occur unless one feels very helpless. He clarifies that we are not inherently helpless, but our blind desires make us feel that way. Otherwise, no one is helpless. There is no issue with desires themselves, as long as they are not blind. A desire that leads you from darkness to light is auspicious. Depression arises when you ask for something where it cannot be found, and then feel dejected when you don't receive it. This is not wisdom. Depression is not a physical injury inflicted from the outside; it is a mental event. At the core of this event lies ignorance and the desires born from it. You want something that cannot happen, like demanding the sun at midnight or seeking consciousness after drinking alcohol. When these impossible desires are not fulfilled, you feel bad. When this feeling of being bad is repeated, you label that state as depression. He advises that if something is right, one should stick to it. If something is false and illusory, one should leave it and move forward. There is no place for depression in this process. If your desire or goal in life is real, beautiful, and leads you towards truth and freedom, then you should advance. If the things you are attached to are foolish, it is in your best interest to accept their foolishness and at least stop desiring them. He suggests that one should either have the courage to move on from foolish things or, if stuck, at least abandon the hope of attaining something high from them. Where there is no desire, there can be no sadness. Without desire, there can be no frustration.