Acharya Prashant clarifies the concept of meditation and concentration as discussed in Vivek Chudamani. He explains that the 'inmost essence' or the heart is not something that can be felt as a sensation, because whatever is felt belongs to the mind. Meditation is not about retreating from the world or bringing the mind back to an 'I am' idea; rather, it is about understanding that the mind and eyes are always looking for something beyond the material objects they perceive. He emphasizes that the human condition is one of dislocation, constantly seeking a home, and meditation is the act of looking fully into where one is without trying to escape.